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Simultaneously, sympathetic nervous system activity measured by HR variability and the rate-pressure-product were also elevated, and increases in HR, systolic BP and sympathetic nervous system activity were still observed even with a concomitant L-NMMA-infusion [38]

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Nevertheless, PS translocation to the outer leaflet of the phospholipid bilayer, a hallmark of eryptosis, can frequently occur without caspase-3 recruitment, primarily in response to Ca 2+ overload [84]

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